Investigation of Mass Transfer in Generalized Power Law Blood Flow through Multiple Stenosed Artery

Authors

  • Kannigah Thirunanasambantham Department of Mathematical Sciences, Faculty of Science, Universiti Teknologi Malaysia,81310, Johor Bahru, Malaysia
  • Zuhaila Ismail Department of Mathematical Sciences, Faculty of Science, Universiti Teknologi Malaysia,81310, Johor Bahru, Malaysia
  • Lim Yeou Jiann Department of Mathematical Sciences, Faculty of Science, Universiti Teknologi Malaysia,81310, Johor Bahru, Malaysia
  • Amnani Shamjuddin Chemical Reaction Engineering Group (CREG), Faculty of Chemical and Energy Engineering, Universiti Teknologi Malaysia, 81310, Johor Bahru, Malaysia
  • Yahaya Shagaiya Daniel Department of Mathematical Sciences, Faculty of Science, Kaduna State University, Nigeria

DOI:

https://doi.org/10.37934/iccm.1.1.5274

Keywords:

Mass transfer, multiple stenosis, generalized power law, COMSOL multiphysics

Abstract

Multiple stenosis refers to the deposition of plaque in an arterial lumen resulting from the development of atherosclerosis. In the presence of stenosis, the arterial wall narrows, thereby limiting blood flow and nutrient delivery to other organs and tissues. This study investigates mass transfer in a generalised power-law blood flow through an artery with multiple stenoses. COMSOL Multiphysics is used to simulate and analyse the mass transfer and blood flow through the stenosed artery. The results demonstrate that the severity of stenosis alters blood flow and mass concentration in the blood. The diffusion rate decreases at the stenotic region as the severity increases. The study demonstrates a twice increase in velocity and mass accumulation at the stenotic region. Findings show that the distance between multiple stenoses significantly impacts the formation of the recirculation zone. The mass concentration rises, and the diffusion flux reduces significantly. These insights provide guidance for optimising drug delivery through stenosed arteries, making it possible to develop advanced treatments for diseases associated with stenosis.

Author Biographies

Kannigah Thirunanasambantham, Department of Mathematical Sciences, Faculty of Science, Universiti Teknologi Malaysia,81310, Johor Bahru, Malaysia

kannigah@graduate.utm.my

Zuhaila Ismail, Department of Mathematical Sciences, Faculty of Science, Universiti Teknologi Malaysia,81310, Johor Bahru, Malaysia

zuhaila@utm.my

Amnani Shamjuddin, Chemical Reaction Engineering Group (CREG), Faculty of Chemical and Energy Engineering, Universiti Teknologi Malaysia, 81310, Johor Bahru, Malaysia

jiann@utm.my

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Published

2025-03-10

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Section

Articles