Analysis of Patient Adherence to the Consumption of Single (Amlodipine) and Combination (Amlodipine + Captopril) Antihypertensive Medication through the Provision of Drug Information Services at the Kubang Jaya Community Health Center

Abstract

The pharmacological treatment of hypertension is a multifaceted process that involves the use of antihypertensive medications to lower and control blood pressure. In previous studies, patient adherence has been reported to play an essential role in achieving successful medication outcomes and can be improved by providing Drug Information Services (DIS) to enhance the understanding of medication instructions. Therefore, this study aimed to assess the effect of providing DIS on patient adherence to the consumption of single (amlodipine) and combination (amlodipine + captopril) antihypertensive medication at the Technical Implementation Unit of the Kubang Jaya Community Health Center. A non-experimental approach with a cross-sectional design was used, and respondents who fulfilled the inclusion criteria were divided into the DIS and non-DIS groups. After a 10-day medication period, respondents were given questionnaires to assess their adherence to the consumption of amlodipine and amlodipine + captopril medication. Mann-Whitney analysis showed a p-value of 0.000 (α<0.05), indicating the presence of a significant difference in adherence between the DIS and non-DIS groups. Based on the Chi-Square analysis results, a p-value of 0.000 (α<0.05) was obtained, showing that sex, education, occupation, and age significantly affected the medication adherence in hypertensive patients. However, there was no significant difference in the effects of consuming amlodipine and amlodipine + captopril antihypertensive medications. The provision of clear and informative DIS had a positive effect on patient adherence to both amlodipine and amlodipine + captopril antihypertensive medications.